Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.997
hemD
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.990
hemF
Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
 0.975
XCC2092
Oxygen-independent coproporphyrinogen III oxidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
 
 0.957
cysG-3
Siroheme synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
    
 0.951
hemB
Delta-aminolevulinic acid dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the ALAD family.
 
 
 0.940
hemL
Glutamate-1-semialdehyde 2,1-aminomutase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
  
 0.938
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.933
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.930
cysG-2
uroporphyrin-III C-methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
    
 0.914
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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