| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XCC2833 | bioA-2 | XCC2833 | XCC2884 | Synthetase/amidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.783 |
| XCC2833 | rmrB | XCC2833 | XCC2342 | Synthetase/amidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Transport protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the major facilitator superfamily. | 0.811 |
| XCC2833 | rmrB-2 | XCC2833 | XCC3487 | Synthetase/amidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | MFS transporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.811 |
| XCC2833 | yhdG-3 | XCC2833 | XCC4220 | Synthetase/amidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Amino acid transporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.810 |
| XCC2885 | bioA-2 | XCC2885 | XCC2884 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.818 |
| bioA-2 | XCC2833 | XCC2884 | XCC2833 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Synthetase/amidase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.783 |
| bioA-2 | XCC2885 | XCC2884 | XCC2885 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.818 |
| bioA-2 | bioB | XCC2884 | XCC0388 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.957 |
| bioA-2 | bioC | XCC2884 | XCC0383 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.832 |
| bioA-2 | bioC-2 | XCC2884 | XCC1678 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthesis protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.787 |
| bioA-2 | bioD | XCC2884 | XCC0587 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.997 |
| bioA-2 | bioF | XCC2884 | XCC0387 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.994 |
| bioA-2 | rmrB | XCC2884 | XCC2342 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Transport protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the major facilitator superfamily. | 0.785 |
| bioA-2 | rmrB-2 | XCC2884 | XCC3487 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | MFS transporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.785 |
| bioA-2 | yhdG-3 | XCC2884 | XCC4220 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Amino acid transporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.785 |
| bioB | bioA-2 | XCC0388 | XCC2884 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.957 |
| bioB | bioC | XCC0388 | XCC0383 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.954 |
| bioB | bioC-2 | XCC0388 | XCC1678 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Biotin synthesis protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.778 |
| bioB | bioD | XCC0388 | XCC0587 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.999 |
| bioB | bioF | XCC0388 | XCC0387 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.983 |