| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XCC2885 | bioA-2 | XCC2885 | XCC2884 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.799 |
| XCC2885 | cysQ | XCC2885 | XCC2882 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Sulfite synthesis pathway protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.691 |
| XCC2885 | metF | XCC2885 | XCC0314 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the methylenetetrahydrofolate reductase family. | 0.671 |
| XCC2885 | metF-2 | XCC2885 | XCC0739 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the methylenetetrahydrofolate reductase family. | 0.722 |
| XCC2885 | metH2 | XCC2885 | XCC1511 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.774 |
| XCC2885 | metK | XCC2885 | XCC0761 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.717 |
| XCC2885 | nudE | XCC2885 | XCC2883 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | ADP compounds hydrolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.697 |
| XCC2885 | panC | XCC2885 | XCC1769 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.696 |
| XCC2885 | prmA | XCC2885 | XCC0512 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.762 |
| XCC2885 | sahH | XCC2885 | XCC0752 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.777 |
| bioA-2 | XCC2885 | XCC2884 | XCC2885 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.799 |
| bioA-2 | cysQ | XCC2884 | XCC2882 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Sulfite synthesis pathway protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.658 |
| bioA-2 | nudE | XCC2884 | XCC2883 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | ADP compounds hydrolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.604 |
| cysQ | XCC2885 | XCC2882 | XCC2885 | Sulfite synthesis pathway protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.691 |
| cysQ | bioA-2 | XCC2882 | XCC2884 | Sulfite synthesis pathway protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.658 |
| cysQ | nudE | XCC2882 | XCC2883 | Sulfite synthesis pathway protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | ADP compounds hydrolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.860 |
| metF | XCC2885 | XCC0314 | XCC2885 | 5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the methylenetetrahydrofolate reductase family. | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.671 |
| metF | metF-2 | XCC0314 | XCC0739 | 5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the methylenetetrahydrofolate reductase family. | 5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the methylenetetrahydrofolate reductase family. | 0.919 |
| metF | metH2 | XCC0314 | XCC1511 | 5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the methylenetetrahydrofolate reductase family. | 5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.982 |
| metF | metK | XCC0314 | XCC0761 | 5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the methylenetetrahydrofolate reductase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.869 |