Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
sdhA
Succinate dehydrogenase flavoprotein subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.991
sdhB
Succinate dehydrogenase iron-sulfur protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.989
odhA
Oxoglutarate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 0.987
sdhC
Succinate dehydrogenase membrane anchor subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.979
sucB
Dihydrolipoamide S-succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.976
phdB
Dihydrolipoamide acetyltranferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.942
XCC3588
CoA tranferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
   
 0.939
sdhD
Succinate dehydrogenase membrane anchor subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.930
prpB
Carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
    
 0.922
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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