| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XCC0018 | XCC3263 | XCC0018 | XCC3263 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.427 |
| XCC1407 | XCC3263 | XCC1407 | XCC3263 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.427 |
| XCC2562 | XCC3263 | XCC2562 | XCC3263 | Integral membrane protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.427 |
| XCC3263 | XCC0018 | XCC3263 | XCC0018 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.427 |
| XCC3263 | XCC1407 | XCC3263 | XCC1407 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.427 |
| XCC3263 | XCC2562 | XCC3263 | XCC2562 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Integral membrane protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.427 |
| XCC3263 | XCC3264 | XCC3263 | XCC3264 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.803 |
| XCC3263 | folD | XCC3263 | XCC2185 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Bifunctional methylenetetrahydrofolate dehydrogenase/ methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.942 |
| XCC3263 | gltB | XCC3263 | XCC0032 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.440 |
| XCC3263 | pheT | XCC3263 | XCC2458 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | phenylalanyl-tRNA synthetase beta chain; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.544 |
| XCC3263 | purN | XCC3263 | XCC2791 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 5'-phosphoribosylglycinamide transformylase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.935 |
| XCC3263 | purT | XCC3263 | XCC1137 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.906 |
| XCC3263 | rpiA | XCC3263 | XCC3265 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.660 |
| XCC3264 | XCC3263 | XCC3264 | XCC3263 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.803 |
| XCC3264 | rpiA | XCC3264 | XCC3265 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.690 |
| folD | XCC3263 | XCC2185 | XCC3263 | Bifunctional methylenetetrahydrofolate dehydrogenase/ methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.942 |
| folD | gltB | XCC2185 | XCC0032 | Bifunctional methylenetetrahydrofolate dehydrogenase/ methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Glutamate synthase, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.527 |
| folD | purN | XCC2185 | XCC2791 | Bifunctional methylenetetrahydrofolate dehydrogenase/ methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 5'-phosphoribosylglycinamide transformylase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.980 |
| folD | purT | XCC2185 | XCC1137 | Bifunctional methylenetetrahydrofolate dehydrogenase/ methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.907 |
| folD | rpiA | XCC2185 | XCC3265 | Bifunctional methylenetetrahydrofolate dehydrogenase/ methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.447 |