STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdcBThreonine dehydratase catabolic; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (372 aa)    
Predicted Functional Partners:
ilvG
Acetolactate synthase isozyme II large subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 0.979
thrC
Threonine synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.968
ilvM
Acetolactate synthase isozyme II small subunit; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.965
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
 
 0.952
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.932
ilvA
Threonine dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
  
 
0.923
XCC0460
Threonine aldolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
   
 
 0.923
sdaA
L-serine dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.923
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.922
cysB
Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
0.919
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.