Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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acsAcetyl coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (647 aa)    
Predicted Functional Partners:
prpC
Citrate synthase 2; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the citrate synthase family.
  
 0.950
gltA
Citrate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the citrate synthase family.
  
 0.950
ppa-2
solute:Na+ symporter; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.949
mls
Malate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
   
 0.946
XCC3588
CoA tranferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 0.932
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.931
yfcY
acyl-CoA thiolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.928
atoB
acetoacetyl-CoA thiolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.928
accC-2
Biotin carboxylase subunit of acetyl CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.918
acyP
Acylphosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
  
 0.916
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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