Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KDS89296.1Homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)    
Predicted Functional Partners:
KDS89294.1
Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.800
KDS89295.1
Methyltransferase type 12; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.713
arcA
Arginine deiminase; Catalyzes the degradation of arginine to citruline and ammonia; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.677
KDS85635.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.563
KDS89297.1
F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.557
KDS89298.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.557
KDS89299.1
Nucleotide pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.557
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
       0.515
KDS89293.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.506
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.446
Your Current Organism:
Streptomyces fradiae
NCBI taxonomy Id: 1906
Other names: ATCC 10745, ATCC 19760, Actinomyces fradii, BCRC 12196, CBS 498.68, CCM 3174, CCRC 12196, CCRC:12196, CECT 3197, DSM 40063, HAMBI 965, HUT 6095, IFO 12773, IFO 3718, IMET 42051, IMI 061202, ISP 5063, JCM 4133, JCM 4579, JCM 4824 [[Streptomyces roseoflavus]], KCTC 9760, NBRC 12773, NBRC 13439 [[Streptomyces roseoflavus]], NBRC 3718, NCIMB 11005, NCIMB 8233, NRRL B-2789 [[Streptomyces roseoflavus]], NRRL-ISP 5063, PCM 2330, RIA 97, S. fradiae, Streptomyces fradiae subsp. fradiae, Streptomyces fradii, Streptomyces roseiflavus, Streptomyces roseoflavus, Streptomyces sp. NEAE-82, UNIQEM 146, VKM Ac-150, VKM Ac-151, VKM Ac-152, VKM Ac-764
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