Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (313 aa)    
Predicted Functional Partners:
coxB
Cytochrome C oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.982
KDS85142.1
Cytochrome B561; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.982
KDS88214.1
Cytochrome B561; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.980
KDS89499.1
Cytochrome C oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.957
KDS88473.1
Cytochrome C oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.957
KDS86080.1
Cytochrome C oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.957
ctaD
Cytochrome C oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
 
 
 0.957
KDS84268.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.884
KDS88474.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.803
KDS85145.1
Ubiquinol-cytochrome c reductase cytochrome b subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.766
Your Current Organism:
Streptomyces fradiae
NCBI taxonomy Id: 1906
Other names: ATCC 10745, ATCC 19760, Actinomyces fradii, BCRC 12196, CBS 498.68, CCM 3174, CCRC 12196, CCRC:12196, CECT 3197, DSM 40063, HAMBI 965, HUT 6095, IFO 12773, IFO 3718, IMET 42051, IMI 061202, ISP 5063, JCM 4133, JCM 4579, JCM 4824 [[Streptomyces roseoflavus]], KCTC 9760, NBRC 12773, NBRC 13439 [[Streptomyces roseoflavus]], NBRC 3718, NCIMB 11005, NCIMB 8233, NRRL B-2789 [[Streptomyces roseoflavus]], NRRL-ISP 5063, PCM 2330, RIA 97, S. fradiae, Streptomyces fradiae subsp. fradiae, Streptomyces fradii, Streptomyces roseiflavus, Streptomyces roseoflavus, Streptomyces sp. NEAE-82, UNIQEM 146, VKM Ac-150, VKM Ac-151, VKM Ac-152, VKM Ac-764
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