node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KDS86881.1 | KDS88140.1 | SFRA_16605 | SFRA_10475 | Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ubiquitin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.738 |
KDS86881.1 | arc | SFRA_16605 | SFRA_10465 | Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.805 |
KDS86881.1 | pafA | SFRA_16605 | SFRA_10490 | Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.750 |
KDS86881.1 | prcA | SFRA_16605 | SFRA_10485 | Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.998 |
KDS86881.1 | prcB | SFRA_16605 | SFRA_10480 | Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.991 |
KDS88140.1 | KDS86881.1 | SFRA_10475 | SFRA_16605 | Ubiquitin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.738 |
KDS88140.1 | arc | SFRA_10475 | SFRA_10465 | Ubiquitin; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.999 |
KDS88140.1 | pafA | SFRA_10475 | SFRA_10490 | Ubiquitin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.864 |
KDS88140.1 | prcA | SFRA_10475 | SFRA_10485 | Ubiquitin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.998 |
KDS88140.1 | prcB | SFRA_10475 | SFRA_10480 | Ubiquitin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.998 |
KDS88145.1 | KDS88146.1 | SFRA_10500 | SFRA_10505 | Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.775 |
KDS88145.1 | KDS88147.1 | SFRA_10500 | SFRA_10510 | Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.748 |
KDS88145.1 | KDS88148.1 | SFRA_10500 | SFRA_10515 | Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.748 |
KDS88145.1 | pafA | SFRA_10500 | SFRA_10490 | Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.733 |
KDS88146.1 | KDS88145.1 | SFRA_10505 | SFRA_10500 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.775 |
KDS88146.1 | KDS88147.1 | SFRA_10505 | SFRA_10510 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
KDS88146.1 | KDS88148.1 | SFRA_10505 | SFRA_10515 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.836 |
KDS88146.1 | arc | SFRA_10505 | SFRA_10465 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.449 |
KDS88146.1 | pafA | SFRA_10505 | SFRA_10490 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.794 |
KDS88146.1 | prcA | SFRA_10505 | SFRA_10485 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.571 |