Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ligBATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)    
Predicted Functional Partners:
KDS87656.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.902
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.885
KDS85539.1
DNA repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.849
KDS88154.1
5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.823
KDS85538.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.809
KDS89884.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.808
KDS85834.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.786
KDS84623.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.667
KDS83943.1
Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.651
KDS85000.1
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.643
Your Current Organism:
Streptomyces fradiae
NCBI taxonomy Id: 1906
Other names: ATCC 10745, ATCC 19760, Actinomyces fradii, BCRC 12196, CBS 498.68, CCM 3174, CCRC 12196, CCRC:12196, CECT 3197, DSM 40063, HAMBI 965, HUT 6095, IFO 12773, IFO 3718, IMET 42051, IMI 061202, ISP 5063, JCM 4133, JCM 4579, JCM 4824 [[Streptomyces roseoflavus]], KCTC 9760, NBRC 12773, NBRC 13439 [[Streptomyces roseoflavus]], NBRC 3718, NCIMB 11005, NCIMB 8233, NRRL B-2789 [[Streptomyces roseoflavus]], NRRL-ISP 5063, PCM 2330, RIA 97, S. fradiae, Streptomyces fradiae subsp. fradiae, Streptomyces fradii, Streptomyces roseiflavus, Streptomyces roseoflavus, Streptomyces sp. NEAE-82, UNIQEM 146, VKM Ac-150, VKM Ac-151, VKM Ac-152, VKM Ac-764
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