Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KDS85906.1Dienelactone hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)    
Predicted Functional Partners:
KDS89271.1
Toxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.534
KDS85905.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.511
KDS87022.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.491
ppnK
Inorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
   0.480
KDS89438.1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.473
KDS84470.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.473
KDS89718.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.444
KDS87125.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.438
KDS89270.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.418
KDS89269.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.403
Your Current Organism:
Streptomyces fradiae
NCBI taxonomy Id: 1906
Other names: ATCC 10745, ATCC 19760, Actinomyces fradii, BCRC 12196, CBS 498.68, CCM 3174, CCRC 12196, CCRC:12196, CECT 3197, DSM 40063, HAMBI 965, HUT 6095, IFO 12773, IFO 3718, IMET 42051, IMI 061202, ISP 5063, JCM 4133, JCM 4579, JCM 4824 [[Streptomyces roseoflavus]], KCTC 9760, NBRC 12773, NBRC 13439 [[Streptomyces roseoflavus]], NBRC 3718, NCIMB 11005, NCIMB 8233, NRRL B-2789 [[Streptomyces roseoflavus]], NRRL-ISP 5063, PCM 2330, RIA 97, S. fradiae, Streptomyces fradiae subsp. fradiae, Streptomyces fradii, Streptomyces roseiflavus, Streptomyces roseoflavus, Streptomyces sp. NEAE-82, UNIQEM 146, VKM Ac-150, VKM Ac-151, VKM Ac-152, VKM Ac-764
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.