STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alkBDNA alkylation damage repair protein AlkB; Dioxygenase that repairs alkylated DNA and RNA containing 3- methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha- ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) (By s [...] (220 aa)    
Predicted Functional Partners:
CC_0261
Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
    0.655
CC_0333
Conserved hypothetical protein; Identified by Glimmer2; putative.
      
 0.559
CC_0776
Conserved hypothetical protein; Identified by Glimmer2; putative.
      
 0.559
CC_0709
Ada regulatory protein, internal deletion; Identified by match to PFAM protein family HMM PF01035.
 
  
 0.537
dnaK
dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
   0.494
uvrA
Excinuclease ABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
     
 0.454
CC_2174
Magnesium transporter; Acts as a magnesium transporter.
 
  
 0.442
CC_3729
Ada regulatory protein; Identified by match to PFAM protein family HMM PF01035.
 
  
 0.401
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.