node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CC_0521 | CC_1740 | CC_0521 | CC_1740 | Identified by match to protein family HMM; Belongs to the P(II) protein family. | Nitrogen regulation protein NR(II); Identified by match to protein family HMM. | 0.732 |
CC_0521 | CC_3607 | CC_0521 | CC_3607 | Identified by match to protein family HMM; Belongs to the P(II) protein family. | Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645. | 0.489 |
CC_0521 | glnD | CC_0521 | CC_0013 | Identified by match to protein family HMM; Belongs to the P(II) protein family. | [protein-pII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.604 |
CC_1339 | CC_1740 | CC_1339 | CC_1740 | Nitrogen regulatory protein P-II 2; Identified by match to protein family HMM; Belongs to the P(II) protein family. | Nitrogen regulation protein NR(II); Identified by match to protein family HMM. | 0.732 |
CC_1339 | CC_3607 | CC_1339 | CC_3607 | Nitrogen regulatory protein P-II 2; Identified by match to protein family HMM; Belongs to the P(II) protein family. | Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645. | 0.498 |
CC_1339 | glnD | CC_1339 | CC_0013 | Nitrogen regulatory protein P-II 2; Identified by match to protein family HMM; Belongs to the P(II) protein family. | [protein-pII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.645 |
CC_1740 | CC_0521 | CC_1740 | CC_0521 | Nitrogen regulation protein NR(II); Identified by match to protein family HMM. | Identified by match to protein family HMM; Belongs to the P(II) protein family. | 0.732 |
CC_1740 | CC_1339 | CC_1740 | CC_1339 | Nitrogen regulation protein NR(II); Identified by match to protein family HMM. | Nitrogen regulatory protein P-II 2; Identified by match to protein family HMM; Belongs to the P(II) protein family. | 0.732 |
CC_1740 | CC_1968 | CC_1740 | CC_1968 | Nitrogen regulation protein NR(II); Identified by match to protein family HMM. | Nitrogen regulatory protein P-II 1; Identified by match to protein family HMM; Belongs to the P(II) protein family. | 0.972 |
CC_1740 | CC_3607 | CC_1740 | CC_3607 | Nitrogen regulation protein NR(II); Identified by match to protein family HMM. | Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645. | 0.409 |
CC_1740 | glnD | CC_1740 | CC_0013 | Nitrogen regulation protein NR(II); Identified by match to protein family HMM. | [protein-pII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.550 |
CC_1968 | CC_1740 | CC_1968 | CC_1740 | Nitrogen regulatory protein P-II 1; Identified by match to protein family HMM; Belongs to the P(II) protein family. | Nitrogen regulation protein NR(II); Identified by match to protein family HMM. | 0.972 |
CC_1968 | CC_3607 | CC_1968 | CC_3607 | Nitrogen regulatory protein P-II 1; Identified by match to protein family HMM; Belongs to the P(II) protein family. | Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645. | 0.510 |
CC_1968 | glnD | CC_1968 | CC_0013 | Nitrogen regulatory protein P-II 1; Identified by match to protein family HMM; Belongs to the P(II) protein family. | [protein-pII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.965 |
CC_3607 | CC_0521 | CC_3607 | CC_0521 | Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645. | Identified by match to protein family HMM; Belongs to the P(II) protein family. | 0.489 |
CC_3607 | CC_1339 | CC_3607 | CC_1339 | Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645. | Nitrogen regulatory protein P-II 2; Identified by match to protein family HMM; Belongs to the P(II) protein family. | 0.498 |
CC_3607 | CC_1740 | CC_3607 | CC_1740 | Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645. | Nitrogen regulation protein NR(II); Identified by match to protein family HMM. | 0.409 |
CC_3607 | CC_1968 | CC_3607 | CC_1968 | Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645. | Nitrogen regulatory protein P-II 1; Identified by match to protein family HMM; Belongs to the P(II) protein family. | 0.510 |
CC_3607 | glnD | CC_3607 | CC_0013 | Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645. | [protein-pII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.549 |
CC_3607 | glnE | CC_3607 | CC_2753 | Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645. | Glutamate-ammonia-ligase adenylyltransferase, putative; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the sig [...] | 0.485 |