| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CC_0050 | CC_1033 | CC_0050 | CC_1033 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | C-5 cytosine-specific DNA methylase; Identified by match to protein family HMM. | 0.918 |
| CC_0050 | CC_2137 | CC_0050 | CC_2137 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.957 |
| CC_0050 | CC_2138 | CC_0050 | CC_2138 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Similar to SP:P37586 GB:X52093; identified by sequence similarity; putative. | 0.959 |
| CC_0050 | CC_2140 | CC_0050 | CC_2140 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | 5,10-methylenetetrahydrofolate reductase; Identified by match to TIGR protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family. | 0.827 |
| CC_0050 | CC_2279 | CC_0050 | CC_2279 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.900 |
| CC_0050 | CC_3168 | CC_0050 | CC_3168 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | Methionine-gamma-lyase; Identified by match to PFAM protein family HMM PF01053. | 0.922 |
| CC_0050 | CC_3626 | CC_0050 | CC_3626 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | DNA-cytosine methyltransferase; Identified by match to protein family HMM; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.918 |
| CC_0050 | ahcY | CC_0050 | CC_0257 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.912 |
| CC_0050 | metE | CC_0050 | CC_0482 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.979 |
| CC_0050 | trmB | CC_0050 | CC_0049 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | Conserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.816 |
| CC_1033 | CC_0050 | CC_1033 | CC_0050 | C-5 cytosine-specific DNA methylase; Identified by match to protein family HMM. | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | 0.918 |
| CC_1033 | CC_3626 | CC_1033 | CC_3626 | C-5 cytosine-specific DNA methylase; Identified by match to protein family HMM. | DNA-cytosine methyltransferase; Identified by match to protein family HMM; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.975 |
| CC_1033 | ahcY | CC_1033 | CC_0257 | C-5 cytosine-specific DNA methylase; Identified by match to protein family HMM. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.905 |
| CC_2137 | CC_0050 | CC_2137 | CC_0050 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | 0.957 |
| CC_2137 | CC_2138 | CC_2137 | CC_2138 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Similar to SP:P37586 GB:X52093; identified by sequence similarity; putative. | 0.999 |
| CC_2137 | CC_2140 | CC_2137 | CC_2140 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5,10-methylenetetrahydrofolate reductase; Identified by match to TIGR protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family. | 0.993 |
| CC_2137 | CC_2279 | CC_2137 | CC_2279 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.900 |
| CC_2137 | CC_3168 | CC_2137 | CC_3168 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine-gamma-lyase; Identified by match to PFAM protein family HMM PF01053. | 0.920 |
| CC_2137 | ahcY | CC_2137 | CC_0257 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.954 |
| CC_2137 | metE | CC_2137 | CC_0482 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.967 |