STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_0061Identified by match to PFAM protein family HMM PF00881. (195 aa)    
Predicted Functional Partners:
rutD
Hydrolase, alpha/beta hydrolase fold family; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation. Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
  
 
 0.924
CC_0062
NifU-like domain protein; Identified by match to protein family HMM.
  
    0.623
rutA
Conserved hypothetical protein; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity).
 
  
 0.570
CC_0059
Identified by match to protein family HMM.
  
    0.566
CC_1169
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.547
rutB
Isochorismatase family protein; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity); Belongs to the isochorismatase family. RutB subfamily.
 
  
 0.536
CC_0058
Ribosomal-protein-alanine acetyltransferase, putative; Identified by match to protein family HMM.
       0.529
CC_0060
Hypothetical protein; Identified by Glimmer2; putative.
       0.479
fur
Ferric uptake regulation protein; Identified by match to PFAM protein family HMM PF01475; Belongs to the Fur family.
  
  
 0.476
CC_2244
ABC-2 type transporter; Identified by match to PFAM protein family HMM PF01061.
  
  
 0.470
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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