node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CC_1347 | hemC | CC_1347 | CC_0072 | Delta-aminolevulinic acid dehydratase; Identified by match to PFAM protein family HMM PF00490; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
CC_1347 | hemE | CC_1347 | CC_3763 | Delta-aminolevulinic acid dehydratase; Identified by match to PFAM protein family HMM PF00490; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen III to yield coproporphyrinogen III. | 0.830 |
CC_1347 | hemF | CC_1347 | CC_0506 | Delta-aminolevulinic acid dehydratase; Identified by match to PFAM protein family HMM PF00490; Belongs to the ALAD family. | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.536 |
CC_1347 | hemH | CC_1347 | CC_3762 | Delta-aminolevulinic acid dehydratase; Identified by match to PFAM protein family HMM PF00490; Belongs to the ALAD family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family. | 0.502 |
CC_1411 | CC_3761 | CC_1411 | CC_3761 | Oxygen-independent coproporphyrinogen III oxidase; Identified by match to TIGR protein family HMM TIGR00538; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.919 |
CC_1411 | hemC | CC_1411 | CC_0072 | Oxygen-independent coproporphyrinogen III oxidase; Identified by match to TIGR protein family HMM TIGR00538; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.462 |
CC_1411 | hemE | CC_1411 | CC_3763 | Oxygen-independent coproporphyrinogen III oxidase; Identified by match to TIGR protein family HMM TIGR00538; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen III to yield coproporphyrinogen III. | 0.955 |
CC_1411 | hemF | CC_1411 | CC_0506 | Oxygen-independent coproporphyrinogen III oxidase; Identified by match to TIGR protein family HMM TIGR00538; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.935 |
CC_3761 | CC_1411 | CC_3761 | CC_1411 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Oxygen-independent coproporphyrinogen III oxidase; Identified by match to TIGR protein family HMM TIGR00538; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.919 |
CC_3761 | hemE | CC_3761 | CC_3763 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen III to yield coproporphyrinogen III. | 0.888 |
CC_3761 | hemF | CC_3761 | CC_0506 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.955 |
CC_3761 | hemH | CC_3761 | CC_3762 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family. | 0.988 |
aroE | hemF | CC_0003 | CC_0506 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.654 |
ctaA | ctaB | CC_1374 | CC_3405 | Cytochrome c oxidase assembly protein, putative; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. | Protoheme IX farnesyl transferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | 0.998 |
ctaA | hemC | CC_1374 | CC_0072 | Cytochrome c oxidase assembly protein, putative; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.689 |
ctaA | hemF | CC_1374 | CC_0506 | Cytochrome c oxidase assembly protein, putative; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.714 |
ctaA | hemH | CC_1374 | CC_3762 | Cytochrome c oxidase assembly protein, putative; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family. | 0.691 |
ctaB | ctaA | CC_3405 | CC_1374 | Protoheme IX farnesyl transferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Cytochrome c oxidase assembly protein, putative; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily. | 0.998 |
ctaB | hemF | CC_3405 | CC_0506 | Protoheme IX farnesyl transferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.493 |
ctaB | hemH | CC_3405 | CC_3762 | Protoheme IX farnesyl transferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family. | 0.931 |