STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_0776Conserved hypothetical protein; Identified by Glimmer2; putative. (483 aa)    
Predicted Functional Partners:
CC_3111
Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.
  
    0.769
CC_2531
Identified by match to protein family HMM.
   
  
 0.735
CC_3567
Identified by match to PFAM protein family HMM PF01557.
      
 0.731
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
   
  
 0.714
alkB
DNA alkylation damage repair protein AlkB; Dioxygenase that repairs alkylated DNA and RNA containing 3- methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha- ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) (By s [...]
      
 0.559
CC_1801
4-coumarate--CoA ligase, putative; Identified by match to protein family HMM.
  
 
   0.548
CC_1817
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.539
CC_3096
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.498
CC_3568
Identified by match to protein family HMM.
      
 0.466
CC_0775
Hypothetical protein; Identified by Glimmer2; putative.
       0.453
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.