Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CC_0776Conserved hypothetical protein; Identified by Glimmer2; putative. (483 aa)    
Predicted Functional Partners:
CC_3111
Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.
  
     0.767
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
   
  
 0.734
CC_1801
4-coumarate--CoA ligase, putative; Identified by match to protein family HMM.
  
 
   0.545
CC_1817
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.539
alkB
DNA alkylation damage repair protein AlkB; Dioxygenase that repairs alkylated DNA and RNA containing 3- methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha- ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) (By s [...]
      
 0.526
CC_3096
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.490
CC_0775
Hypothetical protein; Identified by Glimmer2; putative.
       0.453
CC_0773
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.436
CC_0777
L-sorbosone dehydrogenase; Similar to PID:893353; identified by sequence similarity; putative.
  
    0.434
CC_0774
Monooxygenase, flavin-binding family; Identified by match to PFAM protein family HMM PF00743.
  
    0.415
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
Server load: low (22%) [HD]