STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xylDDehydratase, IlvD/Edd family; Catalyzes the dehydration of D-xylonate to 2-dehydro-3-deoxy- D-arabinonate during D-xylose degradation. Can also dehydrate D- gluconate, with similar catalytic efficiency. Has weak activity with D- galactonate, D-fuconate and L-arabinonate. (595 aa)    
Predicted Functional Partners:
CC_0820
Smp-30/Cgr1 family protein; Similar to GB:AL009126; identified by sequence similarity; putative.
 
  
 0.989
CC_0823
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.955
CC_0822
Aldehyde dehydrogenase; Identified by match to protein family HMM; Belongs to the aldehyde dehydrogenase family.
  
 
 0.887
CC_0967
Oxidoreductase, Gfo/Idh/MocA family; Identified by match to protein family HMM.
 
   
 0.833
CC_3607
Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645.
  
  
 0.808
CC_2791
Fatty aldehyde dehydrogenase; Identified by match to protein family HMM.
  
 
 0.803
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.761
ispG
gcpE protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
      
 0.750
CC_2100
Acetolactate synthase, large subunit; Identified by match to TIGR protein family HMM TIGR00118.
  
 0.742
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
 
  
 0.733
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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