node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CC_1382 | CC_1397 | CC_1382 | CC_1397 | Aminotransferase, class I; Identified by match to protein family HMM. | Phospho-2-dehydro-3-deoxyheptonate aldolase, class I; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.741 |
CC_1382 | parE1 | CC_1382 | CC_0873 | Aminotransferase, class I; Identified by match to protein family HMM. | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD1 but no other ParD or RelB antitoxin. Low levels of wild-type toxin in the absence of antitoxin decreases the rate of cell growth, and results in death or loss of colony formation abilities and greatly elongated cells. Low levels of a mutant missing the last 4 residues leads to loss of cell division while cell elongation continues. | 0.513 |
CC_1397 | CC_1382 | CC_1397 | CC_1382 | Phospho-2-dehydro-3-deoxyheptonate aldolase, class I; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Aminotransferase, class I; Identified by match to protein family HMM. | 0.741 |
CC_1397 | parE1 | CC_1397 | CC_0873 | Phospho-2-dehydro-3-deoxyheptonate aldolase, class I; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD1 but no other ParD or RelB antitoxin. Low levels of wild-type toxin in the absence of antitoxin decreases the rate of cell growth, and results in death or loss of colony formation abilities and greatly elongated cells. Low levels of a mutant missing the last 4 residues leads to loss of cell division while cell elongation continues. | 0.513 |
parD1 | parD2 | CC_0874 | CC_1054 | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE1, but no other RelE or ParE toxin. May act as a DNA gyrase inhibitor (By similarity). | Hypothetical protein; Antitoxin component of a non-functional type II toxin- antitoxin (TA system). Does not neutralize the effect of any of the RelE or ParE toxins. | 0.739 |
parD1 | parD4 | CC_0874 | CC_2985 | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE1, but no other RelE or ParE toxin. May act as a DNA gyrase inhibitor (By similarity). | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE4, but no other RelE or ParE toxin. | 0.895 |
parD1 | parE | CC_0874 | CC_1974 | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE1, but no other RelE or ParE toxin. May act as a DNA gyrase inhibitor (By similarity). | Topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.744 |
parD1 | parE1 | CC_0874 | CC_0873 | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE1, but no other RelE or ParE toxin. May act as a DNA gyrase inhibitor (By similarity). | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD1 but no other ParD or RelB antitoxin. Low levels of wild-type toxin in the absence of antitoxin decreases the rate of cell growth, and results in death or loss of colony formation abilities and greatly elongated cells. Low levels of a mutant missing the last 4 residues leads to loss of cell division while cell elongation continues. | 0.999 |
parD1 | parE3 | CC_0874 | CC_2756 | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE1, but no other RelE or ParE toxin. May act as a DNA gyrase inhibitor (By similarity). | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD3 but no other ParD or RelB antitoxin. | 0.861 |
parD1 | parE4 | CC_0874 | CC_2984 | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE1, but no other RelE or ParE toxin. May act as a DNA gyrase inhibitor (By similarity). | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD4 but no other ParD or RelB antitoxin. | 0.886 |
parD1 | prmC | CC_0874 | CC_0875 | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE1, but no other RelE or ParE toxin. May act as a DNA gyrase inhibitor (By similarity). | hemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.572 |
parD2 | parD1 | CC_1054 | CC_0874 | Hypothetical protein; Antitoxin component of a non-functional type II toxin- antitoxin (TA system). Does not neutralize the effect of any of the RelE or ParE toxins. | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE1, but no other RelE or ParE toxin. May act as a DNA gyrase inhibitor (By similarity). | 0.739 |
parD2 | parE | CC_1054 | CC_1974 | Hypothetical protein; Antitoxin component of a non-functional type II toxin- antitoxin (TA system). Does not neutralize the effect of any of the RelE or ParE toxins. | Topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.763 |
parD2 | parE1 | CC_1054 | CC_0873 | Hypothetical protein; Antitoxin component of a non-functional type II toxin- antitoxin (TA system). Does not neutralize the effect of any of the RelE or ParE toxins. | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD1 but no other ParD or RelB antitoxin. Low levels of wild-type toxin in the absence of antitoxin decreases the rate of cell growth, and results in death or loss of colony formation abilities and greatly elongated cells. Low levels of a mutant missing the last 4 residues leads to loss of cell division while cell elongation continues. | 0.879 |
parD2 | parE3 | CC_1054 | CC_2756 | Hypothetical protein; Antitoxin component of a non-functional type II toxin- antitoxin (TA system). Does not neutralize the effect of any of the RelE or ParE toxins. | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD3 but no other ParD or RelB antitoxin. | 0.864 |
parD2 | parE4 | CC_1054 | CC_2984 | Hypothetical protein; Antitoxin component of a non-functional type II toxin- antitoxin (TA system). Does not neutralize the effect of any of the RelE or ParE toxins. | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD4 but no other ParD or RelB antitoxin. | 0.516 |
parD4 | parD1 | CC_2985 | CC_0874 | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE4, but no other RelE or ParE toxin. | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE1, but no other RelE or ParE toxin. May act as a DNA gyrase inhibitor (By similarity). | 0.895 |
parD4 | parE1 | CC_2985 | CC_0873 | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE4, but no other RelE or ParE toxin. | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD1 but no other ParD or RelB antitoxin. Low levels of wild-type toxin in the absence of antitoxin decreases the rate of cell growth, and results in death or loss of colony formation abilities and greatly elongated cells. Low levels of a mutant missing the last 4 residues leads to loss of cell division while cell elongation continues. | 0.855 |
parD4 | parE3 | CC_2985 | CC_2756 | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE4, but no other RelE or ParE toxin. | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD3 but no other ParD or RelB antitoxin. | 0.411 |
parD4 | parE4 | CC_2985 | CC_2984 | Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE4, but no other RelE or ParE toxin. | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD4 but no other ParD or RelB antitoxin. | 0.967 |