STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_0894acetyl-CoA acetyltransferase; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)    
Predicted Functional Partners:
CC_1431
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.999
CC_0076
Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.
 
 0.996
CC_3189
Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.
 
 0.996
CC_0715
3-hydroxybutyryl-CoA dehydrogenase; Identified by match to PFAM protein family HMM PF00725.
 0.970
CC_1813
Identified by match to PFAM protein family HMM PF00378.
  
 0.961
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.941
CC_0467
3-hydroxy-3-methylglutarate-CoA lyase; Identified by match to protein family HMM.
  
 
 0.923
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.922
CC_1765
Malate synthase; Identified by match to PFAM protein family HMM PF01274; Belongs to the malate synthase family.
   
 
 0.921
CC_0265
Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 
0.920
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.