STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flbDTranscriptional regulator FlbD; Activation of sigma-54-dependent flagellar gene promoters and strong negative autoregulatory effects on its own promoter. The synthesis and function of FlbD in C.crescentus is controlled by an internal cell-cycle clock. (455 aa)    
Predicted Functional Partners:
fliF
Flagellar M-ring protein; The M ring may be actively involved in energy transduction.
 
  
 0.959
flbE
flbE protein; Similar to GB:M98855 SP:Q04953 PID:144249; identified by sequence similarity; putative.
 
  
 0.930
fliX
fliX protein; Required in an early step of flagellar assembly.
  
   
 0.915
fliG
Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
 
  
 0.912
CC_3579
Transcriptional regulator, internal deletion; Similar to GB:M90471 SP:P28614 PID:141888; identified by sequence similarity; putative.
 
    
 0.900
fliN
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity). Belongs to the FliN/MopA/SpaO family.
 
  
 0.880
flhA
Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
 
  
 0.853
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes. This sigma factor is required for the de novo biogenesis of both flagellum and stalk, and for polar morphogenesis and normal cell division. It may not be involved in nitrogen assimilation.
 
  
 0.800
flgE
Flagellar hook protein; Identified by match to protein family HMM.
  
  
 0.783
CC_2058
Hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.731
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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