STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (303 aa)    
Predicted Functional Partners:
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
   
 0.940
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.935
CC_3620
Identified by match to TIGR protein family HMM TIGR00232; Belongs to the transketolase family.
  
 0.928
CC_2615
Inosine-uridine preferring nucleoside hydrolase; Identified by match to PFAM protein family HMM PF01156.
  
 0.915
CC_0085
Phosphoglucomutase; Identified by match to protein family HMM.
   
 0.912
CC_2264
Identified by match to protein family HMM.
  
 
 0.907
CC_0859
Sugar ABC transporter, periplasmic sugar-binding protein; Identified by match to protein family HMM.
 
  
 0.806
CC_1928
Inosine-uridine preferring nucleoside hydrolase; Identified by match to PFAM protein family HMM PF01156.
 
  
 0.802
CC_0861
Sugar ABC transporter, permease protein; Similar to GB:L10328 SP:P04984 GB:M13169 PID:147514 PID:290600; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.760
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
  
 0.720
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.