node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CC_0061 | CC_1169 | CC_0061 | CC_1169 | Identified by match to PFAM protein family HMM PF00881. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.547 |
CC_0061 | CC_1170 | CC_0061 | CC_1170 | Identified by match to PFAM protein family HMM PF00881. | Identified by match to PFAM protein family HMM PF00857. | 0.404 |
CC_0061 | rutA | CC_0061 | CC_2798 | Identified by match to PFAM protein family HMM PF00881. | Conserved hypothetical protein; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity). | 0.570 |
CC_0061 | rutB | CC_0061 | CC_2795 | Identified by match to PFAM protein family HMM PF00881. | Isochorismatase family protein; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity); Belongs to the isochorismatase family. RutB subfamily. | 0.536 |
CC_0061 | rutC | CC_0061 | CC_2796 | Identified by match to PFAM protein family HMM PF00881. | Conserved hypothetical protein; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation. | 0.422 |
CC_0061 | rutD | CC_0061 | CC_2797 | Identified by match to PFAM protein family HMM PF00881. | Hydrolase, alpha/beta hydrolase fold family; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation. Belongs to the AB hydrolase superfamily. Hydrolase RutD family. | 0.924 |
CC_1166 | CC_1169 | CC_1166 | CC_1169 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.517 |
CC_1166 | CC_1170 | CC_1166 | CC_1170 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Identified by match to PFAM protein family HMM PF00857. | 0.517 |
CC_1169 | CC_0061 | CC_1169 | CC_0061 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Identified by match to PFAM protein family HMM PF00881. | 0.547 |
CC_1169 | CC_1166 | CC_1169 | CC_1166 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.517 |
CC_1169 | CC_1170 | CC_1169 | CC_1170 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Identified by match to PFAM protein family HMM PF00857. | 0.946 |
CC_1169 | CC_2275 | CC_1169 | CC_2275 | Conserved hypothetical protein; Identified by Glimmer2; putative. | NADH:riboflavin 5'-phosphate oxidoreductase; Identified by match to protein family HMM. | 0.550 |
CC_1169 | CC_2659 | CC_1169 | CC_2659 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Hypothetical protein; Identified by Glimmer2; putative. | 0.721 |
CC_1169 | rutA | CC_1169 | CC_2798 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity). | 0.913 |
CC_1169 | rutB | CC_1169 | CC_2795 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Isochorismatase family protein; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity); Belongs to the isochorismatase family. RutB subfamily. | 0.980 |
CC_1169 | rutC | CC_1169 | CC_2796 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation. | 0.650 |
CC_1169 | rutD | CC_1169 | CC_2797 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Hydrolase, alpha/beta hydrolase fold family; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation. Belongs to the AB hydrolase superfamily. Hydrolase RutD family. | 0.739 |
CC_1169 | upp | CC_1169 | CC_2268 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.900 |
CC_1170 | CC_0061 | CC_1170 | CC_0061 | Identified by match to PFAM protein family HMM PF00857. | Identified by match to PFAM protein family HMM PF00881. | 0.404 |
CC_1170 | CC_1166 | CC_1170 | CC_1166 | Identified by match to PFAM protein family HMM PF00857. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.517 |