node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CC_0266 | CC_3303 | CC_0266 | CC_3303 | Identified by match to protein family HMM; Belongs to the Nudix hydrolase family. | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.900 |
CC_0266 | CC_3304 | CC_0266 | CC_3304 | Identified by match to protein family HMM; Belongs to the Nudix hydrolase family. | NAD(P) transhydrogenase, alpha2 subunit; Similar to GB:U01158 GB:U05294 PID:436914 PID:452573; identified by sequence similarity; putative. | 0.900 |
CC_0266 | CC_3305 | CC_0266 | CC_3305 | Identified by match to protein family HMM; Belongs to the Nudix hydrolase family. | NAD(P) transhydrogenase, alpha subunit; Identified by match to PFAM protein family HMM PF01262. | 0.900 |
CC_0266 | MazG | CC_0266 | CC_1747 | Identified by match to protein family HMM; Belongs to the Nudix hydrolase family. | Mazg protein; Identified by match to protein family HMM. | 0.911 |
CC_0266 | cobB | CC_0266 | CC_3480 | Identified by match to protein family HMM; Belongs to the Nudix hydrolase family. | Transcriptional regulator, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | 0.908 |
CC_0266 | nadD | CC_0266 | CC_3431 | Identified by match to protein family HMM; Belongs to the Nudix hydrolase family. | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.906 |
CC_0266 | nadE | CC_0266 | CC_3619 | Identified by match to protein family HMM; Belongs to the Nudix hydrolase family. | NAD(+) synthetase, putative; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.912 |
CC_0266 | nadK | CC_0266 | CC_1221 | Identified by match to protein family HMM; Belongs to the Nudix hydrolase family. | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.905 |
CC_1220 | nadK | CC_1220 | CC_1221 | Hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.718 |
CC_3303 | CC_0266 | CC_3303 | CC_0266 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Identified by match to protein family HMM; Belongs to the Nudix hydrolase family. | 0.900 |
CC_3303 | CC_3304 | CC_3303 | CC_3304 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD(P) transhydrogenase, alpha2 subunit; Similar to GB:U01158 GB:U05294 PID:436914 PID:452573; identified by sequence similarity; putative. | 0.999 |
CC_3303 | CC_3305 | CC_3303 | CC_3305 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD(P) transhydrogenase, alpha subunit; Identified by match to PFAM protein family HMM PF01262. | 0.999 |
CC_3303 | MazG | CC_3303 | CC_1747 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Mazg protein; Identified by match to protein family HMM. | 0.903 |
CC_3303 | cobB | CC_3303 | CC_3480 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Transcriptional regulator, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | 0.901 |
CC_3303 | nadD | CC_3303 | CC_3431 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.903 |
CC_3303 | nadE | CC_3303 | CC_3619 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD(+) synthetase, putative; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.934 |
CC_3303 | nadK | CC_3303 | CC_1221 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.907 |
CC_3304 | CC_0266 | CC_3304 | CC_0266 | NAD(P) transhydrogenase, alpha2 subunit; Similar to GB:U01158 GB:U05294 PID:436914 PID:452573; identified by sequence similarity; putative. | Identified by match to protein family HMM; Belongs to the Nudix hydrolase family. | 0.900 |
CC_3304 | CC_3303 | CC_3304 | CC_3303 | NAD(P) transhydrogenase, alpha2 subunit; Similar to GB:U01158 GB:U05294 PID:436914 PID:452573; identified by sequence similarity; putative. | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
CC_3304 | CC_3305 | CC_3304 | CC_3305 | NAD(P) transhydrogenase, alpha2 subunit; Similar to GB:U01158 GB:U05294 PID:436914 PID:452573; identified by sequence similarity; putative. | NAD(P) transhydrogenase, alpha subunit; Identified by match to PFAM protein family HMM PF01262. | 0.999 |