node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CC_0747 | CC_1914 | CC_0747 | CC_1914 | Identified by match to protein family HMM. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.967 |
CC_0747 | CC_3494 | CC_0747 | CC_3494 | Identified by match to protein family HMM. | Identified by match to protein family HMM. | 0.867 |
CC_0747 | bamA | CC_0747 | CC_1915 | Identified by match to protein family HMM. | Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.777 |
CC_1909 | CC_1914 | CC_1909 | CC_1914 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.675 |
CC_1909 | bamA | CC_1909 | CC_1915 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.835 |
CC_1909 | fabZ | CC_1909 | CC_1912 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.906 |
CC_1909 | frr | CC_1909 | CC_1920 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.438 |
CC_1909 | lpxA | CC_1909 | CC_1911 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.995 |
CC_1909 | lpxD | CC_1909 | CC_1913 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.997 |
CC_1909 | lpxI | CC_1909 | CC_1910 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Conserved hypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to form 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the beta-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Can functionally complement lpxH deficiency in E.coli. Cannot use CDP- diacylglycerol as substrate; Belongs to the LpxI family. | 0.979 |
CC_1909 | mmpA | CC_1909 | CC_1916 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Membrane-associated zinc metalloprotease, putative; Involved in the regulated intramembrane proteolysis (RIP) of the short isoform of PodJ protein (PodJS), during the swarmer-to- stalked transition. The cleavage occurs near or within the single transmembrane of PodJS thereby releasing the N-terminal segment into the cytoplasm for subsequent degradation. It contributes to preserve asymmetry in the next cell cycle through sequential degradation. | 0.537 |
CC_1914 | CC_0747 | CC_1914 | CC_0747 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Identified by match to protein family HMM. | 0.967 |
CC_1914 | CC_1909 | CC_1914 | CC_1909 | Conserved hypothetical protein; Identified by Glimmer2; putative. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.675 |
CC_1914 | CC_3494 | CC_1914 | CC_3494 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Identified by match to protein family HMM. | 0.967 |
CC_1914 | bamA | CC_1914 | CC_1915 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.951 |
CC_1914 | fabZ | CC_1914 | CC_1912 | Conserved hypothetical protein; Identified by Glimmer2; putative. | (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.784 |
CC_1914 | frr | CC_1914 | CC_1920 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.630 |
CC_1914 | lpxA | CC_1914 | CC_1911 | Conserved hypothetical protein; Identified by Glimmer2; putative. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.796 |
CC_1914 | lpxD | CC_1914 | CC_1913 | Conserved hypothetical protein; Identified by Glimmer2; putative. | UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.880 |
CC_1914 | lpxI | CC_1914 | CC_1910 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to form 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the beta-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Can functionally complement lpxH deficiency in E.coli. Cannot use CDP- diacylglycerol as substrate; Belongs to the LpxI family. | 0.686 |