STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarate hydratase, class II, aerobic; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)    
Predicted Functional Partners:
SdhA
Succinate dehydrogenase, flavoprotein subunit; Identified by match to protein family HMM; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.997
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.983
CC_2622
NADP-dependent malic enzyme; Identified by match to PFAM protein family HMM PF01515.
  
 
 0.967
SdhB
Succinate dehydrogenase, iron-sulfur protein; Identified by match to protein family HMM; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.967
CC_3549
NADP-dependent malic enzyme; Identified by match to PFAM protein family HMM PF01515.
  
 
 0.967
CC_1765
Malate synthase; Identified by match to PFAM protein family HMM PF01274; Belongs to the malate synthase family.
    
 0.961
CC_3529
Succinate dehydrogenase, cytochrome b556 subunit; Identified by match to PFAM protein family HMM PF01127.
  
 
 0.960
CC_3528
Succinate dehydrogenase, hydrophobic membrane anchor protein, putative; Similar to GP:3273340; identified by sequence similarity; putative.
  
 
 0.921
CC_2531
Identified by match to protein family HMM.
  
 0.917
CC_3567
Identified by match to PFAM protein family HMM PF01557.
  
 0.917
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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