STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_2179propionyl-CoA carboxylase, alpha subunit; Identified by match to PFAM protein family HMM PF00289. (669 aa)    
Predicted Functional Partners:
CC_1975
propionyl-CoA carboxylase, beta subunit; Identified by match to protein family HMM.
 0.998
CC_2170
propionyl-CoA carboxylase, beta subunit, putative; Identified by match to protein family HMM.
 
 0.983
CC_3214
Carbamoyl-phosphate synthase/carboxyl transferase; Identified by match to PFAM protein family HMM PF00289.
 
0.982
CC_1727
Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.981
CC_2999
Citrate lyase, beta subunit, putative; Similar to SP:O53078; identified by sequence similarity; putative; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.923
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.920
CC_1883
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.916
CC_2168
acetyl/propionyl-CoA carboxylase, alpha subunit; Identified by match to PFAM protein family HMM PF00289.
  
  
 
0.910
CC_1933
Lactoylglutathione lyase, putative; Identified by match to protein family HMM.
  
 
 0.909
CC_1302
Methylmalonate-semialdehyde dehydrogenase, putative; Identified by match to protein family HMM.
   
 
 0.906
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.