STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_2274Methylmalonate-semialdehyde dehydrogenase, putative; Identified by match to protein family HMM. (498 aa)    
Predicted Functional Partners:
CC_1354
3-hydroxyisobutyrate dehydrogenase; Identified by match to protein family HMM; Belongs to the HIBADH-related family.
 
 0.944
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.940
CC_1574
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.932
CC_3143
Omega-amino acid--pyruvate aminotransferase; Identified by match to protein family HMM; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.922
CC_0076
Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.
  
 0.918
CC_0419
Aldehyde dehydrogenase; Identified by match to protein family HMM.
  
  
 
0.917
CC_1884
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
    
 0.909
CC_1883
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
    
 0.908
CC_0077
Fatty oxidation complex, beta subunit, putative; Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.907
CC_0779
Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.907
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.