Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CC_2299Fatty acid transport protein, putative; Identified by match to protein family HMM. (635 aa)    
Predicted Functional Partners:
CC_2300
Phospho-2-dehydro-3-deoxyheptonate aldolase, class II; Identified by match to PFAM protein family HMM PF01474.
      0.737
lpxC
UDP-3-O-3-hydroxymyristoyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
      
 0.721
CC_2298
Identified by match to protein family HMM.
 
   0.674
CC_2171
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.612
CC_0076
Fatty oxidation complex, alpha subunit; Identified by match to PFAM protein family HMM PF00725.
 
 
 0.517
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 0.476
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.474
CC_1764
Isocitrate lyase; Identified by match to protein family HMM.
   
  
 0.468
CC_1733
Aas bifunctional protein, putative; Identified by match to protein family HMM.
  
    0.464
CC_1163
Acyl carrier protein, putative; Identified by match to PFAM protein family HMM PF00550.
  
 
 0.427
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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