STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_2373methylmalonyl-CoA mutase, beta subunit; Identified by match to protein family HMM. (483 aa)    
Predicted Functional Partners:
CC_2374
methylmalonyl-CoA mutase, alpha subunit; Identified by match to PFAM protein family HMM PF01642.
 
0.996
CC_3081
methylmalonyl-CoA mutase, alpha subunit; Identified by match to PFAM protein family HMM PF01642.
 
 0.994
CC_1933
Lactoylglutathione lyase, putative; Identified by match to protein family HMM.
 
  
 0.978
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.910
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.907
CC_2483
LAO transporter binding protein kinase, putative; May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone (By similarity).
  
 0.867
CC_3724
Coenzyme A transferase, putative; Similar to GB:L21902 SP:P38946 PID:347071; identified by sequence similarity; putative.
    
 0.824
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
     
 0.814
CC_1906
Citrate synthase; Identified by match to protein family HMM; Belongs to the citrate synthase family.
     
 0.807
CC_3642
Citrate synthase; Identified by match to protein family HMM; Belongs to the citrate synthase family.
     
 0.807
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.