STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_24103-carboxy-cis,cis-muconate cycloisomerase; Identified by match to protein family HMM. (382 aa)    
Predicted Functional Partners:
CC_2411
3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase; Identified by match to protein family HMM.
 
 0.999
CC_2408
Protocatechuate 3,4-dioxygenase, beta subunit; Identified by match to PFAM protein family HMM PF00775.
 
 
 0.995
CC_2409
Protocatechuate 3,4-dioxygenase, alpha subunit; Identified by match to protein family HMM.
 
 
 0.995
CC_2404
P-hydroxybenzoate hydroxylase; Identified by match to PFAM protein family HMM PF01360.
 
  
 0.924
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 
 0.898
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.871
purD
Phosphoribosylamine--glycine ligase; Identified by match to PFAM protein family HMM PF01071.
  
 
 0.849
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by match to TIGR protein family HMM TIGR00355.
  
 
 0.845
purM
Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to PFAM protein family HMM PF00586.
  
 
 0.835
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.825
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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