STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_2522Isocitrate dehydrogenase, NADP-dependent; Identified by match to TIGR protein family HMM TIGR00127; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (403 aa)    
Predicted Functional Partners:
CC_3667
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.996
Kgd
2-oxoglutarate dehydrogenase, E1 component; Identified by match to TIGR protein family HMM TIGR00239.
   
 
 0.974
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.943
CC_1906
Citrate synthase; Identified by match to protein family HMM; Belongs to the citrate synthase family.
  
 
 0.939
CC_3642
Citrate synthase; Identified by match to protein family HMM; Belongs to the citrate synthase family.
  
 
 0.938
CC_3643
Citrate synthase; Identified by match to protein family HMM.
  
 
 0.938
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.923
CC_3607
Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645.
  
 
 0.898
folD
FolD bifunctional protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.887
CC_1534
Aspartate aminotransferase; Identified by match to protein family HMM.
   
 0.836
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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