STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (425 aa)    
Predicted Functional Partners:
CC_2533
4-hydroxyphenylpyruvate dioxygenase; Identified by match to protein family HMM.
 
 0.999
CC_3568
Identified by match to protein family HMM.
 
 
 0.995
CC_2531
Identified by match to protein family HMM.
 
  
 0.966
CC_3567
Identified by match to PFAM protein family HMM PF01557.
  
  
 0.917
PhhB
Pterin-4-alpha-carbinolamine dehydratase; Identified by match to PFAM protein family HMM PF01329.
  
  
 0.902
phhA
Phenylalanine-4-hydroxylase; Identified by match to protein family HMM.
 
  
 0.887
CC_0333
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
  
 0.714
CC_0776
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
  
 0.714
hisC2
Histidinol-phosphate aminotransferase; Identified by match to protein family HMM; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
   
 0.563
CC_2188
Transcriptional regulator, MarR family; Identified by match to protein family HMM.
 
   
 0.534
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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