STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_2659Hypothetical protein; Identified by Glimmer2; putative. (423 aa)    
Predicted Functional Partners:
CC_3385
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0246 family.
  
    0.859
CC_2660
TonB-dependent receptor; Identified by match to protein family HMM.
 
     0.811
CC_1169
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
    0.721
CC_2132
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
     0.670
CC_1170
Identified by match to PFAM protein family HMM PF00857.
 
     0.532
rutA
Conserved hypothetical protein; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity).
 
    0.442
rutB
Isochorismatase family protein; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity); Belongs to the isochorismatase family. RutB subfamily.
 
     0.437
CC_3309
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.419
CC_2661
Transcriptional regulator, GntR family; Identified by match to protein family HMM.
 
     0.405
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.