STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parD4Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE4, but no other RelE or ParE toxin. (96 aa)    
Predicted Functional Partners:
parE4
Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD4 but no other ParD or RelB antitoxin.
 
 
 0.967
parD1
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin ParE1, but no other RelE or ParE toxin. May act as a DNA gyrase inhibitor (By similarity).
 
  
 0.895
parE1
Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD1 but no other ParD or RelB antitoxin. Low levels of wild-type toxin in the absence of antitoxin decreases the rate of cell growth, and results in death or loss of colony formation abilities and greatly elongated cells. Low levels of a mutant missing the last 4 residues leads to loss of cell division while cell elongation continues.
 
 
 0.855
relE1
Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin RelB1 but no other ParD or RelB antitoxin.
  
 
 0.848
relE4
Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its toxic effect is neutralized by coexpression with cognate antitoxin RelB4 but no other ParD or RelB antitoxin.
  
 
 0.848
relB1
Hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin RelE1, but no other RelE or ParE toxin.
      
 0.759
CC_0445
Transcriptional regulator, GntR family; Identified by match to protein family HMM.
  
    0.471
CC_0536
Transcriptional regulator, GntR family; Identified by match to protein family HMM.
  
    0.463
cobB
Transcriptional regulator, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily.
   
    0.451
CC_2986
Hypothetical protein; Identified by Glimmer2; putative.
       0.447
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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