STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ilvRIsoleucine biosynthesis transcriptional activator; Positively regulates the expression of the ilvD gene while negatively autoregulating its own expression. (296 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase; Identified by match to TIGR protein family HMM TIGR00110.
     
 0.893
fdxA
Identified by match to protein family HMM.
      
 0.787
CC_1621
Transcriptional regulator, LysR family; Identified by match to protein family HMM; Belongs to the LysR transcriptional regulatory family.
  
     0.756
CC_3046
Conserved hypothetical protein; Identified by Glimmer2; putative.
   
 
 0.643
cysC
Sulfate adenylate transferase, subunit 1/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
      
 0.633
CC_0790
Transcriptional regulator, LysR family; Identified by match to protein family HMM; Belongs to the LysR transcriptional regulatory family.
  
     0.551
CC_3607
Glutamate synthase, large subunit; Identified by match to PFAM protein family HMM PF01645.
     
 0.524
CC_2517
Transcriptional regulator, LysR family; Identified by match to protein family HMM; Belongs to the LysR transcriptional regulatory family.
  
     0.496
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen III to yield coproporphyrinogen III.
     
 0.488
CC_2564
Transcriptional regulator, LysR family; Identified by match to protein family HMM; Belongs to the LysR transcriptional regulatory family.
  
    0.474
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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