node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CC_3158 | folE | CC_3158 | CC_0459 | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | GTP cyclohydrolase I; Identified by match to TIGR protein family HMM TIGR00063. | 0.981 |
CC_3158 | queC | CC_3158 | CC_3160 | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.984 |
CC_3158 | queE | CC_3158 | CC_3159 | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
CC_3158 | queF | CC_3158 | CC_2654 | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.867 |
cysC | cysD | CC_1482 | CC_1483 | Sulfate adenylate transferase, subunit 1/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Sulfate adenylate transferase, subunit 2; Identified by match to PFAM protein family HMM PF01507. | 0.999 |
cysC | queE | CC_1482 | CC_3159 | Sulfate adenylate transferase, subunit 1/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.736 |
cysC | ubiG | CC_1482 | CC_0840 | Sulfate adenylate transferase, subunit 1/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.603 |
cysD | cysC | CC_1483 | CC_1482 | Sulfate adenylate transferase, subunit 2; Identified by match to PFAM protein family HMM PF01507. | Sulfate adenylate transferase, subunit 1/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
cysD | queE | CC_1483 | CC_3159 | Sulfate adenylate transferase, subunit 2; Identified by match to PFAM protein family HMM PF01507. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.799 |
cysD | ubiG | CC_1483 | CC_0840 | Sulfate adenylate transferase, subunit 2; Identified by match to PFAM protein family HMM PF01507. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.789 |
dnaG | folE | CC_3049 | CC_0459 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. | GTP cyclohydrolase I; Identified by match to TIGR protein family HMM TIGR00063. | 0.708 |
dnaG | queC | CC_3049 | CC_3160 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.487 |
dnaG | queE | CC_3049 | CC_3159 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.634 |
folE | CC_3158 | CC_0459 | CC_3158 | GTP cyclohydrolase I; Identified by match to TIGR protein family HMM TIGR00063. | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | 0.981 |
folE | dnaG | CC_0459 | CC_3049 | GTP cyclohydrolase I; Identified by match to TIGR protein family HMM TIGR00063. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. | 0.708 |
folE | queC | CC_0459 | CC_3160 | GTP cyclohydrolase I; Identified by match to TIGR protein family HMM TIGR00063. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.843 |
folE | queE | CC_0459 | CC_3159 | GTP cyclohydrolase I; Identified by match to TIGR protein family HMM TIGR00063. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.890 |
moaC | queE | CC_0014 | CC_3159 | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.625 |
queC | CC_3158 | CC_3160 | CC_3158 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | 0.984 |
queC | dnaG | CC_3160 | CC_3049 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. | 0.487 |