| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CC_3157 | CC_3158 | CC_3157 | CC_3158 | Hypothetical protein; Identified by Glimmer2; putative. | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | 0.752 |
| CC_3157 | queC | CC_3157 | CC_3160 | Hypothetical protein; Identified by Glimmer2; putative. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.598 |
| CC_3157 | queE | CC_3157 | CC_3159 | Hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.556 |
| CC_3158 | CC_3157 | CC_3158 | CC_3157 | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | Hypothetical protein; Identified by Glimmer2; putative. | 0.752 |
| CC_3158 | folE | CC_3158 | CC_0459 | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | GTP cyclohydrolase I; Identified by match to TIGR protein family HMM TIGR00063. | 0.981 |
| CC_3158 | queC | CC_3158 | CC_3160 | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.984 |
| CC_3158 | queE | CC_3158 | CC_3159 | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
| CC_3158 | queF | CC_3158 | CC_2654 | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.867 |
| folE | CC_3158 | CC_0459 | CC_3158 | GTP cyclohydrolase I; Identified by match to TIGR protein family HMM TIGR00063. | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | 0.981 |
| folE | queC | CC_0459 | CC_3160 | GTP cyclohydrolase I; Identified by match to TIGR protein family HMM TIGR00063. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.843 |
| folE | queE | CC_0459 | CC_3159 | GTP cyclohydrolase I; Identified by match to TIGR protein family HMM TIGR00063. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.890 |
| folE | ribB | CC_0459 | CC_0887 | GTP cyclohydrolase I; Identified by match to TIGR protein family HMM TIGR00063. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.940 |
| queC | CC_3157 | CC_3160 | CC_3157 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Hypothetical protein; Identified by Glimmer2; putative. | 0.598 |
| queC | CC_3158 | CC_3160 | CC_3158 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to PFAM protein family HMM PF01242. | 0.984 |
| queC | folE | CC_3160 | CC_0459 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | GTP cyclohydrolase I; Identified by match to TIGR protein family HMM TIGR00063. | 0.843 |
| queC | queE | CC_3160 | CC_3159 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
| queC | queF | CC_3160 | CC_2654 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.997 |
| queC | ribB | CC_3160 | CC_0887 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.830 |
| queC | rpmB | CC_3160 | CC_0661 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Ribosomal protein L28; Identified by match to TIGR protein family HMM TIGR00009; Belongs to the bacterial ribosomal protein bL28 family. | 0.809 |
| queC | rpmE | CC_3160 | CC_3275 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | 0.647 |