| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CC_0050 | CC_2137 | CC_0050 | CC_2137 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.957 |
| CC_0050 | CC_2138 | CC_0050 | CC_2138 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Similar to SP:P37586 GB:X52093; identified by sequence similarity; putative. | 0.959 |
| CC_0050 | CC_2279 | CC_0050 | CC_2279 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.900 |
| CC_0050 | CC_3168 | CC_0050 | CC_3168 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | Methionine-gamma-lyase; Identified by match to PFAM protein family HMM PF01053. | 0.922 |
| CC_0050 | metE | CC_0050 | CC_0482 | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.979 |
| CC_1426 | CC_2137 | CC_1426 | CC_2137 | Cysteine synthase; Identified by match to protein family HMM. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.825 |
| CC_1426 | CC_2138 | CC_1426 | CC_2138 | Cysteine synthase; Identified by match to protein family HMM. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Similar to SP:P37586 GB:X52093; identified by sequence similarity; putative. | 0.837 |
| CC_1426 | CC_3168 | CC_1426 | CC_3168 | Cysteine synthase; Identified by match to protein family HMM. | Methionine-gamma-lyase; Identified by match to PFAM protein family HMM PF01053. | 0.931 |
| CC_1426 | CC_3625 | CC_1426 | CC_3625 | Cysteine synthase; Identified by match to protein family HMM. | Cysteine synthase; Identified by match to protein family HMM. | 0.916 |
| CC_1426 | metE | CC_1426 | CC_0482 | Cysteine synthase; Identified by match to protein family HMM. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.830 |
| CC_1426 | metZ | CC_1426 | CC_2238 | Cysteine synthase; Identified by match to protein family HMM. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.964 |
| CC_2137 | CC_0050 | CC_2137 | CC_0050 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosylmethionine synthetase; Identified by match to protein family HMM; Belongs to the AdoMet synthase family. | 0.957 |
| CC_2137 | CC_1426 | CC_2137 | CC_1426 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase; Identified by match to protein family HMM. | 0.825 |
| CC_2137 | CC_2138 | CC_2137 | CC_2138 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Similar to SP:P37586 GB:X52093; identified by sequence similarity; putative. | 0.999 |
| CC_2137 | CC_2279 | CC_2137 | CC_2279 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.900 |
| CC_2137 | CC_3168 | CC_2137 | CC_3168 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine-gamma-lyase; Identified by match to PFAM protein family HMM PF01053. | 0.920 |
| CC_2137 | CC_3625 | CC_2137 | CC_3625 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase; Identified by match to protein family HMM. | 0.826 |
| CC_2137 | metE | CC_2137 | CC_0482 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.967 |
| CC_2137 | metG | CC_2137 | CC_1480 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.901 |
| CC_2137 | metZ | CC_2137 | CC_2238 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.929 |