node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CC_0265 | CC_1432 | CC_0265 | CC_1432 | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. | 0.901 |
CC_0265 | CC_3176 | CC_0265 | CC_3176 | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | 0.599 |
CC_0265 | acsA | CC_0265 | CC_3581 | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.939 |
CC_1432 | CC_0265 | CC_1432 | CC_0265 | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. | 0.901 |
CC_1432 | CC_3176 | CC_1432 | CC_3176 | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | 0.599 |
CC_1432 | acsA | CC_1432 | CC_3581 | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.939 |
CC_3176 | CC_0265 | CC_3176 | CC_0265 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. | 0.599 |
CC_3176 | CC_1432 | CC_3176 | CC_1432 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | Identified by match to protein family HMM; Belongs to the thiolase-like superfamily. Thiolase family. | 0.599 |
CC_3176 | CC_3177 | CC_3176 | CC_3177 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | Transcriptional regulator, AsnC family; Identified by match to protein family HMM. | 0.641 |
CC_3176 | SdhA | CC_3176 | CC_3527 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | Succinate dehydrogenase, flavoprotein subunit; Identified by match to protein family HMM; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.922 |
CC_3176 | acsA | CC_3176 | CC_3581 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.734 |
CC_3176 | aroC | CC_3176 | CC_3154 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.779 |
CC_3176 | fdxA | CC_3176 | CC_0654 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | Identified by match to protein family HMM. | 0.642 |
CC_3176 | hup | CC_3176 | CC_1959 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family. | 0.742 |
CC_3176 | miaA | CC_3176 | CC_2098 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.779 |
CC_3176 | nuoI | CC_3176 | CC_1942 | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | NADH dehydrogenase I, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.620 |
CC_3177 | CC_3176 | CC_3177 | CC_3176 | Transcriptional regulator, AsnC family; Identified by match to protein family HMM. | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | 0.641 |
SdhA | CC_3176 | CC_3527 | CC_3176 | Succinate dehydrogenase, flavoprotein subunit; Identified by match to protein family HMM; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to PFAM protein family HMM PF01558. | 0.922 |
SdhA | acsA | CC_3527 | CC_3581 | Succinate dehydrogenase, flavoprotein subunit; Identified by match to protein family HMM; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.624 |
SdhA | fdxA | CC_3527 | CC_0654 | Succinate dehydrogenase, flavoprotein subunit; Identified by match to protein family HMM; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Identified by match to protein family HMM. | 0.500 |