STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_3250Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (363 aa)    
Predicted Functional Partners:
CC_3248
Glyceraldehyde 3-phosphate dehydrogenase; Identified by match to protein family HMM; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.993
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.988
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.983
pgi
Glucose-6-phosphate isomerase; Identified by match to protein family HMM.
  
 
 0.970
pgk
Phosphoglycerate kinase; Identified by match to protein family HMM; Belongs to the phosphoglycerate kinase family.
  
 
 0.968
fbp
Fructose-1,6-bisphosphatase; Identified by match to protein family HMM.
 
 
 0.964
CC_3620
Identified by match to TIGR protein family HMM TIGR00232; Belongs to the transketolase family.
  
 
 0.962
tal
Transaldolase family protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.959
GlpX
glpX protein; Identified by match to TIGR protein family HMM TIGR00330.
  
 
 0.937
CC_2051
Pyruvate kinase; Identified by match to protein family HMM; Belongs to the pyruvate kinase family.
  
 0.930
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.