STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_3528Succinate dehydrogenase, hydrophobic membrane anchor protein, putative; Similar to GP:3273340; identified by sequence similarity; putative. (139 aa)    
Predicted Functional Partners:
SdhB
Succinate dehydrogenase, iron-sulfur protein; Identified by match to protein family HMM; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.999
SdhA
Succinate dehydrogenase, flavoprotein subunit; Identified by match to protein family HMM; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.999
CC_3529
Succinate dehydrogenase, cytochrome b556 subunit; Identified by match to PFAM protein family HMM PF01127.
 
 0.999
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.987
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.937
fumC
Fumarate hydratase, class II, aerobic; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.921
CC_3140
Succinate-semialdehyde dehydrogenase; Identified by match to protein family HMM; Belongs to the aldehyde dehydrogenase family.
   
 
 0.904
CC_3724
Coenzyme A transferase, putative; Similar to GB:L21902 SP:P38946 PID:347071; identified by sequence similarity; putative.
    
  0.900
Kgd
2-oxoglutarate dehydrogenase, E1 component; Identified by match to TIGR protein family HMM TIGR00239.
  
  
 0.848
argH
Argininosuccinate lyase; Identified by match to TIGR protein family HMM TIGR00838.
   
 
  0.808
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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