STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_3538Helicase, UvrD/Rep family; Identified by match to protein family HMM; Belongs to the helicase family. UvrD subfamily. (1203 aa)    
Predicted Functional Partners:
CC_3537
Hypothetical protein; Identified by Glimmer2; putative.
   
 0.977
recO
Conserved hypothetical protein; Involved in DNA repair and RecF pathway recombination.
 
   
 0.829
CC_3534
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.825
amgK
Conserved hypothetical protein; Sugar kinase that catalyzes the ATP-dependent phosphorylation of N-acetylmuramate (MurNAc) and N-acetylglucosamine (GlcNAc) at its C1 hydroxyl group, leading to MurNAc alpha-1P and GlcNAc alpha-1P, respectively (By similarity). Is likely involved in peptidoglycan recycling as part of a cell wall recycling pathway that bypasses de novo biosynthesis of the peptidoglycan precursor UDP-MurNAc. Is able to complement the fosfomycin sensitivity phenotype of a P.putida mutant lacking amgK.
  
    0.812
murU
Nucleotidyltransferase family protein; Catalyzes the formation of UDP-N-acetylmuramate (UDP-MurNAc), a crucial precursor of the bacterial peptidoglycan cell wall, from UTP and MurNAc-alpha-1P. Is likely involved in peptidoglycan recycling as part of a cell wall recycling pathway that bypasses de novo biosynthesis of the peptidoglycan precursor UDP-MurNAc. Is able to complement the fosfomycin sensitivity phenotype of a P.putida mutant lacking murU.
       0.810
CC_3533
Identified by match to PFAM protein family HMM PF01553.
       0.787
CC_2102
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.745
CC_3705
Hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
 
     0.732
CC_3319
Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the UPF0335 family.
  
     0.694
CC_3639
Identified by match to protein family HMM.
  
     0.691
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.