| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CC_1897 | CC_2953 | CC_1897 | CC_2953 | Glutamine amidotransferase, class I; Identified by match to protein family HMM. | Para-aminobenzoate synthase, component I; Identified by match to PFAM protein family HMM PF00425. | 0.999 |
| CC_1897 | trpA | CC_1897 | CC_3543 | Glutamine amidotransferase, class I; Identified by match to protein family HMM. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.983 |
| CC_1897 | trpB | CC_1897 | CC_3544 | Glutamine amidotransferase, class I; Identified by match to protein family HMM. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.991 |
| CC_1897 | trpC | CC_1897 | CC_1899 | Glutamine amidotransferase, class I; Identified by match to protein family HMM. | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM; Belongs to the TrpC family. | 0.999 |
| CC_1897 | trpD | CC_1897 | CC_1898 | Glutamine amidotransferase, class I; Identified by match to protein family HMM. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
| CC_1897 | trpE | CC_1897 | CC_1895 | Glutamine amidotransferase, class I; Identified by match to protein family HMM. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
| CC_1897 | trpF | CC_1897 | CC_3545 | Glutamine amidotransferase, class I; Identified by match to protein family HMM. | N-(5'-phosphoribosyl)-anthranilate isomerase; Identified by match to protein family HMM; Belongs to the TrpF family. | 0.986 |
| CC_2953 | CC_1897 | CC_2953 | CC_1897 | Para-aminobenzoate synthase, component I; Identified by match to PFAM protein family HMM PF00425. | Glutamine amidotransferase, class I; Identified by match to protein family HMM. | 0.999 |
| CC_2953 | trpA | CC_2953 | CC_3543 | Para-aminobenzoate synthase, component I; Identified by match to PFAM protein family HMM PF00425. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.925 |
| CC_2953 | trpB | CC_2953 | CC_3544 | Para-aminobenzoate synthase, component I; Identified by match to PFAM protein family HMM PF00425. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.941 |
| CC_2953 | trpC | CC_2953 | CC_1899 | Para-aminobenzoate synthase, component I; Identified by match to PFAM protein family HMM PF00425. | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM; Belongs to the TrpC family. | 0.986 |
| CC_2953 | trpD | CC_2953 | CC_1898 | Para-aminobenzoate synthase, component I; Identified by match to PFAM protein family HMM PF00425. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.991 |
| CC_2953 | trpE | CC_2953 | CC_1895 | Para-aminobenzoate synthase, component I; Identified by match to PFAM protein family HMM PF00425. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.850 |
| CC_2953 | trpF | CC_2953 | CC_3545 | Para-aminobenzoate synthase, component I; Identified by match to PFAM protein family HMM PF00425. | N-(5'-phosphoribosyl)-anthranilate isomerase; Identified by match to protein family HMM; Belongs to the TrpF family. | 0.939 |
| CC_3541 | trpA | CC_3541 | CC_3543 | FolC bifunctional protein; Identified by match to protein family HMM; Belongs to the folylpolyglutamate synthase family. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.853 |
| CC_3541 | trpB | CC_3541 | CC_3544 | FolC bifunctional protein; Identified by match to protein family HMM; Belongs to the folylpolyglutamate synthase family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.814 |
| CC_3541 | trpF | CC_3541 | CC_3545 | FolC bifunctional protein; Identified by match to protein family HMM; Belongs to the folylpolyglutamate synthase family. | N-(5'-phosphoribosyl)-anthranilate isomerase; Identified by match to protein family HMM; Belongs to the TrpF family. | 0.827 |
| CC_3541 | usg | CC_3541 | CC_3546 | FolC bifunctional protein; Identified by match to protein family HMM; Belongs to the folylpolyglutamate synthase family. | Usg protein; Probably necessary for the cotranslation of trpF. It may also function as a subunit or stabilizer of phosphoribosylanthranilate isomerase (trpF). | 0.591 |
| hisB | trpA | CC_3734 | CC_3543 | Imidazoleglycerol-phosphate dehydratase; Identified by match to PFAM protein family HMM PF00475. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.815 |
| hisB | trpB | CC_3734 | CC_3544 | Imidazoleglycerol-phosphate dehydratase; Identified by match to PFAM protein family HMM PF00475. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.611 |