STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_3579Transcriptional regulator, internal deletion; Similar to GB:M90471 SP:P28614 PID:141888; identified by sequence similarity; putative. (314 aa)    
Predicted Functional Partners:
flbD
Transcriptional regulator FlbD; Activation of sigma-54-dependent flagellar gene promoters and strong negative autoregulatory effects on its own promoter. The synthesis and function of FlbD in C.crescentus is controlled by an internal cell-cycle clock.
 
    
 0.900
CC_1741
Nitrogen regulation protein NR(I); Identified by match to protein family HMM.
 
    
 0.900
CC_1743
Nitrogen regulation protein NtrX; Identified by match to protein family HMM.
 
    
 0.900
CC_3315
Sigma-54 dependent DNA-binding response regulator; Identified by match to protein family HMM.
 
    
 0.900
CC_3580
Aldehyde dehydrogenase B; Identified by match to protein family HMM; Belongs to the aldehyde dehydrogenase family.
 
 
 0.870
CC_3578
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
    0.509
CC_0860
Sugar ABC transporter, ATP-binding protein; Identified by match to protein family HMM.
   
  
 0.419
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.408
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.