node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CC_3684 | CC_3685 | CC_3684 | CC_3685 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.778 |
CC_3684 | dapF | CC_3684 | CC_3686 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.873 |
CC_3685 | CC_3684 | CC_3685 | CC_3684 | Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.778 |
CC_3685 | dapF | CC_3685 | CC_3686 | Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.781 |
carB | dapF | CC_2900 | CC_3686 | Carbamoyl-phosphate synthase, large subunit; Identified by match to PFAM protein family HMM PF00289. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.911 |
dapD | dapE | CC_0281 | CC_0275 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Identified by match to protein family HMM; Belongs to the transferase hexapeptide repeat family. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.831 |
dapD | dapF | CC_0281 | CC_3686 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Identified by match to protein family HMM; Belongs to the transferase hexapeptide repeat family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.830 |
dapD | lysA | CC_0281 | CC_2213 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Identified by match to protein family HMM; Belongs to the transferase hexapeptide repeat family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.405 |
dapD | murE | CC_0281 | CC_2559 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Identified by match to protein family HMM; Belongs to the transferase hexapeptide repeat family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.407 |
dapE | dapD | CC_0275 | CC_0281 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Identified by match to protein family HMM; Belongs to the transferase hexapeptide repeat family. | 0.831 |
dapE | dapF | CC_0275 | CC_3686 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.935 |
dapF | CC_3684 | CC_3686 | CC_3684 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.873 |
dapF | CC_3685 | CC_3686 | CC_3685 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.781 |
dapF | carB | CC_3686 | CC_2900 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Carbamoyl-phosphate synthase, large subunit; Identified by match to PFAM protein family HMM PF00289. | 0.911 |
dapF | dapD | CC_3686 | CC_0281 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Identified by match to protein family HMM; Belongs to the transferase hexapeptide repeat family. | 0.830 |
dapF | dapE | CC_3686 | CC_0275 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.935 |
dapF | ddl | CC_3686 | CC_2543 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | D-alanine--D-alanine ligase B; Cell wall formation. | 0.810 |
dapF | leuC | CC_3686 | CC_0196 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.832 |
dapF | lysA | CC_3686 | CC_2213 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.956 |
dapF | murE | CC_3686 | CC_2559 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.966 |