STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_3733Carbohydrate kinase, PfkB family; Identified by match to protein family HMM. (365 aa)    
Predicted Functional Partners:
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by match to TIGR protein family HMM TIGR00007.
  
    0.863
hisB
Imidazoleglycerol-phosphate dehydratase; Identified by match to PFAM protein family HMM PF00475.
  
    0.777
hisF
hisF protein (cyclase); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
     
 0.763
hisH
Amidotransferase HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
  
    0.747
hisE
phosphoribosyl-ATP pyrophosphatase; Identified by match to PFAM protein family HMM PF01503.
       0.746
CC_3732
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.606
CC_1301
iolB protein; Similar to SP:P42413 PID:709982 PID:904208 PID:2280501 GB:AL009126; identified by sequence similarity; putative.
  
  
 0.522
CC_1299
iolD protein; Identified by match to protein family HMM; Belongs to the TPP enzyme family.
  
  
 0.516
secE
Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
    0.501
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 
 0.496
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.