STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIR97620.1Enoyl-(acyl carrier protein) reductase. (255 aa)    
Predicted Functional Partners:
fabD
Malonyl CoA-acyl carrier protein transacylase.
 
  
 0.962
accD
Putative acetyl carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
  
 0.955
AIR98247.1
Acetyl CoA carboxylase subunits alpha/beta.
 
  
 0.955
fabG1
3-oxoacyl-[acyl-carrier-protein] reductase FabG1; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 0.915
accC
Putative Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.886
fabH
3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has a broad substrate specificity for butyryl-CoA > acetyl-CoA > isobutyryl-CoA. Can also prime acyl-CoA. Its substrate specificity determines the biosynthesis of both branched- c [...]
 
  
 0.866
fabH2
3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
  
 0.863
nphT7
Acetoacetyl CoA synthase NphT7.
 
  
 0.850
AIR97452.1
Hypothetical protein; Belongs to the P-Pant transferase superfamily.
  
    0.845
fabF
3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
  
 0.833
Your Current Organism:
Streptomyces glaucescens
NCBI taxonomy Id: 1907
Other names: ATCC 19761, ATCC 23622, Actinomyces glaucescens, BCRC 11478, CBS 499.68, CCRC 11478, CCRC:11478, CECT 3133, DSM 40155, IFO 12774, IMET 43584, INA 8731, ISP 5155, JCM 4377, LMG 19330, LMG:19330, NBRC 12774, NCIMB 9619, NCIMB 9844, NRRL B-2706, NRRL-ISP 5155, S. glaucescens, UNIQEM 147, VKM Ac-617
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