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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
nfoPutative endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (292 aa)    
Predicted Functional Partners:
ung2
Uracil-DNA glycosylase 2; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
  
 
 0.946
AIS01342.1
Exonuclease.
    
 
 0.834
AIR98882.1
Exodeoxyribonuclease III.
    
 
 0.829
AIR97930.1
Glycine oxidase.
       0.723
AIR97931.1
Hypothetical protein.
       0.723
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
       0.723
spk1
Serine/threonine-protein kinase PK-1.
     
 0.679
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
     
 0.678
AIR97929.1
Hypothetical protein.
       0.671
AIR97665.1
Precorrin-4 C11-methyltransferase.
      
 0.670
Your Current Organism:
Streptomyces glaucescens
NCBI taxonomy Id: 1907
Other names: ATCC 19761, ATCC 23622, Actinomyces glaucescens, BCRC 11478, CBS 499.68, CCRC 11478, CCRC:11478, CECT 3133, DSM 40155, IFO 12774, IMET 43584, INA 8731, ISP 5155, JCM 4377, LMG 19330, LMG:19330, NBRC 12774, NCIMB 9619, NCIMB 9844, NRRL B-2706, NRRL-ISP 5155, S. glaucescens, UNIQEM 147, VKM Ac-617
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